ATYPICAL CSF PICTURE IN VIRAL MENINGITIS HSV- TYPE-2

HSV-2 Meningitis Presenting with Acute Hydrocephalus Ultimately Requiring Long Term CSF Diversion

Herpes simplex virus type 1 and 2 can infect the human nervous system causing meningitis and encephalitis. HSV meningitis tends to be benign, but HSF encephalitis can have a high morbidity and mortality despite treatment. We present a case of HSV meningitis leading to hydrocephalus without evidence of encephalitis. The patient had persistent hydrocephalus requiring long term CSF diversion despi...

CSF HSV PCR Testing in Adults and Children with Meningitis and Encephalitis

Seroepidemiological Study of Herpes Simplex Virus Type 2 (HSV-2) Antibody in Shiraz, Iran

Background: Herpes Simplex Virus (HSV) Type 2 is a widespread human infectious agent responsible for persistent and latent infections. Objectives: To estimate the regional seroprevalence of anti HSV-2 antibody in Shiraz, Iran and to investigate the possible correlation of seropositivity with malignant changes in subjects’ Papanicolaou (Pap) tests. Methods: Data were collected in a cross-section...

Neoplastic Meningitis: How MRI and CSF Cytology Are Influenced by CSF Cell Count and Tumor Type

BACKGROUND Although CSF cytology and MRI are standard methods to diagnose neoplastic meningitis (NM), this complication of neoplastic disease remains difficult to detect. We therefore reevaluated the sensitivity of gadolinium (GD)-enhanced MRI and cerebrospinal-fluid (CSF)-cytology and the relevance of tumor type and CSF cell count. METHODS We retrospectively identified 111 cases of NM diagno...

Viral Meningitis

Viral meningitis is a central nervous system (CNS) infection characterized by signs and symptoms of meningeal inflammation in the absence of positive bacterial cultures. The incidence varies with season, and the clinical presentation often includes fever, headache, and nuchal rigidity (stiffness of the neck) accompanied by symptoms typical of the specific causal virus. Viral meningitis is usual...